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Presence of carcinoembryonic antigen in children's colonic mucosa
Author(s) -
Burtin P.,
Sabine M. C.,
Chavanel G.
Publication year - 1972
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910100110
Subject(s) - carcinoembryonic antigen , antigen , immunofluorescence , medicine , pathology , antiserum , intestinal mucosa , gastroenterology , antibody , immunology , cancer
The colonic mucosa of 48 young children, nine of them being over one year, and two being seven years old, was studied for the presence of carcinoembryonic antigen (CEA). In all the cases, immunofluorescence with specific anti CEA antiserum was positive. Phytic extracts of three pools of juvenile colonic mucosae contained an antigen giving an identity reaction with reference CEA. CEA is thus a normal antigen in children's colonic mucosa.