Immunological studies on a hamster‐specific sarcoma virus | Zendy

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Immunological studies on a hamster‐specific sarcoma virus

Author(s) -

Bomford R.

Publication year - 1971

Publication title -

international journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.475

H-Index - 234

eISSN - 1097-0215

pISSN - 0020-7136

DOI - 10.1002/ijc.2910080108

Subject(s) - hamster , rous sarcoma virus , virology , biology , virus , sarcoma , antigen , mesocricetus , viral transformation , oncovirus , microbiology and biotechnology , immunology , pathology , medicine

A hamster‐specific sarcoma virus released from cells of a Harvey murine sarcoma virus (H‐MSV)‐induced hamster tumour is shown to have the hamster leukaemia virus group‐specific (gs) antigen, and hence to be a hamster leukaemia virirs (HaL V) pseudotype of the murine sarcoma virus, H‐MSV (HaLV). The hamster leukaemia virus gs antigen is not detectable in non‐producer H‐MSV (HaLV) transformed hamster cells or in Rous sarcoma virus, polyoma or SV40‐transformed cells. Five out of 6 transplanted hamster tumours were found to contain the HaLV gs antigen.

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