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Immunofluorescent study of alpha‐foetoprotein (αfp) in liver and liver tumours. II. Localization of αfp in the tissues of patients with primary liver cancer (PLC)
Author(s) -
Goussev A. I.,
Engelhardt N. V.,
Masseyeff R.,
Camain R.,
Basteris B.
Publication year - 1971
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910070204
Subject(s) - haematoxylin , pathology , eosin , staining , liver cancer , sinusoid , alpha (finance) , hepatocellular carcinoma , medicine , immunohistochemistry , biology , construct validity , nursing , patient satisfaction
Localization of αfp independent of the presence of serum was demonstrated only in a limited number of tumour cells in αfp‐positive hepatocellular carcinomas. These cells usually formed three‐dimensional groups with a definite tendency to localize near blood vessels and capillaries. Haematoxylin‐eosin staining did not reveal any morphological difference between αfp‐positive and ‐negative tumour cells.