Premium
Recovery from the inhibitory effect of X‐radiation on urethan lung adenomagenesis
Author(s) -
Bartlett Gerald L.
Publication year - 1970
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910060109
Subject(s) - irradiation , thymectomy , lung , adenoma , carcinogen , incidence (geometry) , medicine , nuclear medicine , biology , biochemistry , myasthenia gravis , physics , nuclear physics , optics
Abstract Male (C 2 HfBiHe x Alele)F 1 mice irradiated with 500 R 24 h prior to urethan treatment developed fewer lung adenomas than non‐irradiated, urethan‐treated mice. When irradiation was given two weeks before irrethan treatment, adenoma incidence was the some as in non‐irradiaetd controls, suggesting recovery fromthe tumorinhibitory effrect of radiation. The recovery was not prevented by thymectomy prior to irradiation. Irradiation of female (C 3 HfBiHe × AjHe)F 1 mice with 500 R did no significantly reduce the numver of adenomas induced by urethan.