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Hemolysin production in spleen and peripheral blood cells from normal and leukemic chicks. II. Ultrastructural analysis of the plaque‐forming cells
Author(s) -
Lagerlöf Bengt,
Sundelin Par
Publication year - 1970
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910050310
Subject(s) - spleen , biology , ultrastructure , pathology , precursor cell , leukemia , microbiology and biotechnology , immunology , cell , medicine , genetics
The cells of normal and leukemic chicks producing hemolytic plaques in agar after stimulation with SRBC have been examined ultrastructurally. The plaque‐forming cells from non‐leukemic chicks were generally plasma cells. This was also the case for 21 of 30 plaques formed by spleen or peripheral blood cells from chicks with myeloid leukemia, while in the nine remaining plaques the plaque‐forming cells were very immature blast cells.