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Serum α 1 foeto‐protein (fetuin) in children with malignant ovarian or testicular teratomas. Preliminary results
Author(s) -
Mawas C.,
Kohen M.,
Lemerle J.,
Buffe D.,
Schweisguth O.,
Burtin P.
Publication year - 1969
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910040110
Subject(s) - medicine , fetuin , testicular cancer , cancer , endocrinology , biology , glycoprotein , microbiology and biotechnology
In a study of sera of 93 children bearing various malignant tumours, the authors were able to detect by an immunological test an enthryonal protein, α1 foeto‐protein or fetuin, in one testicular and four ovarian embryonal carcinomas. Children bearing tumours other than malignant teratomas, and control children, gave negative results (with one exception in a normal 3‐day‐old infant). Such an immunological test, therefore, appears to have some diagnostic and prog nostic value which deserves further investigation.