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Chromosome studies on cultured lymphoblast cell lines from cases of new guinea burkitt lymphoma, myeloblastic and lymphoblastic leukaemia and infectious mononucleosis
Author(s) -
Tomkins G. A.
Publication year - 1968
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910030513
Subject(s) - lymphoblast , mononucleosis , cell culture , biology , chromosome , ploidy , lymphoma , virology , microbiology and biotechnology , genetics , immunology , virus , gene
Chromosome analysis of three lymphoblast cell lines from New Guinea Burkitt lymphoma (QIMR‐GOR, QIMR‐AMB/1 and AMB/2), three lymphoblast cell lines from infectious mononucleosis (QIMR‐DAR, QIMR‐STE and QIMR‐GOE) and two lymphoblast cell lines from leukaemia (QIMR‐WIL and QIMR‐FIN) showed abnormalities associated with Group A, C, and G chromosomes. Each cell line contained diploid and near diploid cells. Some of the cell lines also contained pseudodiploid cells. Extra Group C or Group G chromosomes were found in a proportion of cells from some of the cell lines. Abnormal Group A chromosomes were also found. However, no one abnormality could confidently be assigned to a specific source of origin of the cell line studied.