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Studies on carcinogenesis by avian sarcoma viruses: VIII. Glycolysis and cell multiplication
Author(s) -
Temin Howard M.
Publication year - 1968
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910030213
Subject(s) - glycolysis , multiplication (music) , carcinogenesis , biology , limiting , virus , virology , cell culture , sarcoma , tumor cells , cancer research , metabolism , biochemistry , genetics , pathology , cancer , medicine , physics , mechanical engineering , acoustics , engineering
Glycolysis and multiplication were studied in parallel cultures of uninfected and of avian sarcoma virus‐converted chicken and duck cells. It was found that:. 1. In cultures where the amount of serum was limiting for cell multiplication, converted cells multiplied more and glycolyzed more than did uninfected cells. In both types of cultures, the relationship between the rates of glycolysis and of multiplication per culture was similar. 2. In cultures with excess serum and other nutrients, converted cells and uninfected cells multiplied and glycolyzed at the same rate.