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Biological and chemotherapeutic studies on primary mammary tumors in C3H and C3HO mice
Author(s) -
Gelzer J.,
Loustalot P.
Publication year - 1967
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910020212
Subject(s) - mammary gland , chemotherapy , mammary tumor , cancer , rodent , biology , hormone , primary (astronomy) , pathology , cancer research , medicine , oncology , breast cancer , ecology , physics , astronomy
A reproducible chemotherapy assay system using primary mammary tumors in C3H and C3HO mice is described. These tumors, although possibly hormone‐dependent to a minor extent, are not steroid‐sensitive and their response to accepted anti‐cancer compounds follows in general that of classical transplantable rodent tumors.