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Spermidine, spermine and glutathione in Rd/3 sarcoma rats
Author(s) -
Neish W. J. P.,
Key Linda
Publication year - 1967
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910020202
Subject(s) - spermidine , spermine , glutathione , sarcoma , biochemistry , medicine , polyamine , endocrinology , chemistry , biology , pathology , enzyme
Concentrations of the polyamines spermidine and spermine and of glutathione have been studied in livers of normal rats and in livers and tumours of rats bearing Rd/3 sarcoma transplants. In livers of tumour‐bearing rats it was found that the spermidine content increased and glutathione content diminished with increasing tumour size.