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Human papillomavirus infection in a population‐based sample of women in Algiers, Algeria
Author(s) -
Hammouda Doudja,
Clifford Gary M.,
Pallardy Sophie,
Ayyach Ghassan,
Chékiri Asma,
Boudrich Arab,
Snijders Peter J.F.,
van Kemenade Folkert J.,
Meijer Chris J.L.M.,
Bouhadef Anissa,
Zitouni Zahia,
Habib Djamila,
Ikezaren Nadia,
Franceschi Silvia
Publication year - 2011
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.25539
Subject(s) - population , demography , medicine , cervical cancer , hpv infection , human papillomavirus , gynecology , cervical screening , cancer , environmental health , sociology
No data exist on the population prevalence of, nor risk factors for, human papillomavirus (HPV) infection in the predominantly Muslim countries of Northern Africa. Cervical specimens were obtained from 759 married women aged 15–65 years from the general population of Algiers, Algeria. Liquid‐based cytology and HPV DNA detection, using a GP5+/6+‐based polymerase chain reaction assay that detects 44 HPV types, were performed according to the standardized protocol of the International Agency for Research on Cancer HPV Prevalence Surveys. HPV prevalence in the general population was 6.3% (4.0% of high‐risk types), with no significant variation by age. The prevalence of cervical abnormalities was 3.6%. HPV positivity was significantly higher among divorced women, women in polygamous marriages and those reporting husband's extramarital sexual relationships. HPV16/18 accounted for only 15% of HPV‐positive women in the general population, compared with 77% of invasive cervical cancer diagnosed in the same city. In conclusion, we report that HPV infection among married women in Algeria is much lower than in sub‐Saharan Africa and also lower than in the majority of high‐resource countries.