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miRNA control of tumor cell invasion and metastasis
Author(s) -
Baranwal Somesh,
Alahari Suresh K.
Publication year - 2010
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.25014
Subject(s) - microrna , metastasis , biology , cell migration , gene , cancer research , cancer , gene expression , regulation of gene expression , cell , genetics
MicroRNAs have emerged as a novel class of noncoding RNAs that regulate gene expression at the post‐translational level in almost every biological event. A large body of evidence indicates that microRNAs regulate the expression of different genes that play an important role in cancer cell invasion, migration and metastasis. In this review, we briefly describe the role of various miRNAs in invasion, migration and metastasis which are essential steps during cancer progression.