Premium
A prospective analysis of the association between dietary fiber intake and prostate cancer risk in EPIC
Author(s) -
Suzuki Reiko,
Allen Naomi E.,
Key Timothy J.,
Appleby Paul N.,
Tjønneland Anne,
Johnsen Nina Føns,
Jensen Majken K.,
Overvad Kim,
Boeing Heiner,
Pischon Tobias,
Kaaks Rudolf,
Rohrmann Sabine,
Trichopoulou Antonia,
Misirli Gesthimani,
Trichopoulos Dimitrios,
BuenodeMesquita H. Bas,
van Duijnhoven Fränzel,
Sacerdote Carlotta,
Pala Valeria,
Palli Domenico,
Tumino Rosario,
Ardanaz Eva,
Quirós José Ramón,
Larrañaga Nerea,
Sánchez MariaJosé,
Tormo MaríaJosé,
Jakszyn Paula,
Johansson Ingegerd,
Stattin Pär,
Berglund Göran,
Manjer Jonas,
Bingham Sheila,
Khaw KayTee,
Egevad Lars,
Ferrari Pietro,
Jenab Mazda,
Riboli Elio
Publication year - 2008
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.23908
Subject(s) - prostate cancer , medicine , european prospective investigation into cancer and nutrition , confounding , prospective cohort study , dietary fiber , prostate , proportional hazards model , cancer , relative risk , lower risk , risk factor , environmental health , food science , confidence interval , biology
Abstract Few studies have examined the association between dietary fiber intake and prostate cancer risk. We evaluated the association between dietary fiber intake and the risk of prostate cancer among 142,590 men in the European Prospective Investigation into Cancer and Nutrition (EPIC). Consumption of dietary fiber (total, cereal, fruit and vegetable fiber) was estimated by validated dietary questionnaires and calibrated using 24‐hr dietary recalls. Incidence rate ratios were estimated using Cox regression and adjusted for potential confounding factors. During an average of 8.7 years follow‐up, prostate cancer was diagnosed in 2,747 men. Overall, there was no association between dietary fiber intake (total, cereal, fruit or vegetable fiber) and prostate cancer risk, although calibrated intakes of total fiber and fruit fiber were associated with nonstatistically significant reductions in risk. There was no association between fiber derived from cereals or vegetables and risk and no evidence for heterogeneity in any of the risk estimates by stage or grade of disease. Our results suggest that dietary fiber intake is not associated with prostate cancer risk. © 2008 Wiley‐Liss, Inc.