Cutaneous human papillomavirus 88: Remarkable differences in viral load | Zendy

Kullander Johanna | Zendy; Handisurya Alessandra | Zendy; Forslund Ola | Zendy; Geusau Alexandra | Zendy; Kirnbauer Reinhard | Zendy; Dillner Joakim | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Cutaneous human papillomavirus 88: Remarkable differences in viral load

Author(s) -

Kullander Johanna,

Handisurya Alessandra,

Forslund Ola,

Geusau Alexandra,

Kirnbauer Reinhard,

Dillner Joakim

Publication year - 2007

Publication title -

international journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.475

H-Index - 234

eISSN - 1097-0215

pISSN - 0020-7136

DOI - 10.1002/ijc.23115

Subject(s) - actinic keratoses , viral load , pathology , human papillomavirus , basal cell , basal (medicine) , biology , cell , virology , viral disease , virus , medicine , genetics , insulin , endocrinology

A human papillomavirus (HPV) was cloned from a patient with multiple squamous cell carcinomas (SCCs) and identified as HPV88, recently categorized into a new species within the genus Gamma . The HPV88 viral load in an SCC of the index patient exceeded 1 million copies/cell. By contrast, a survey of 447 skin lesions (79 actinic keratoses, 73 seborrhoeic keratoses, 169 basal cell carcinomas and 126 SCCs) and 362 healthy skin biopsies found detectable HPV88 DNA in only 7 specimens. All these had very low viral loads (<1 copy/10 3 cells) implying extreme biological variability in viral load. © 2007 Wiley‐Liss, Inc.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research