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Parity, tubal sterilization, hysterectomy and risk of primary fallopian tube carcinoma in Finland, 1975–2004
Author(s) -
Riska Annika,
Sund Reijo,
Pukkala Eero,
Gissler Mika,
Leminen Arto
Publication year - 2006
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.22491
Subject(s) - medicine , gynecology , odds ratio , hysterectomy , obstetrics , parity (physics) , sterilization (economics) , population , surgery , physics , environmental health , particle physics , monetary economics , economics , foreign exchange market , foreign exchange
We studied the possible relationship among parity, female sterilization, hysterectomy and the risk of primary fallopian tube carcinoma (PFTC) in a case–control study in Finland in cases occurring between 1975 and 2004. A total of 573 PFTC cases were identified from the Finnish Cancer Registry, and10 age‐matched controls per case were randomly selected from the Finnish Central Population Registry. In multivariate analysis (including 189 PFTC cases and 1764 controls) parity was protective: the odds ratio (OR) for 1–2 deliveries was 0.63 (95% CI 0.44–0.91) and for ≥3 deliveries, 0.32 (95% CI 0.19–0.52). The OR for sterilization was 0.74 (95% CI 0.42–1.30) and for hysterectomy 1.27 (95% CI 0.73–2.21). Our findings suggest a possible hormonal background as regards the development of PFTC. © 2006 Wiley‐Liss, Inc.