Premium
A 14;19 TRANSLOCATION IN B‐CELL CHRONIC LYMPHOCYTIC LEUKEMIA: A NEW RECURRING CHROMOSOME ABERRATION
Author(s) -
UESHIMA Yoshimi,
BIRD Mary Lourdes,
VARDIMAN James W.,
ROWLEY Janet D.
Publication year - 1985
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.1985.36.3.287
Subject(s) - chromosomal translocation , prolymphocytic leukemia , chronic lymphocytic leukemia , chromosome analysis , cytogenetics , chromosome , leukemia , medicine , cancer research , biology , pathology , karyotype , immunology , genetics , gene
Four of 30 patients with a diagnosis of B‐CLL or prolymphocytic transformation of CLL, who had an adequate cytogenetic analysis, had abnormalities involving 14q32. Three of the 4 had a translocation involving chr. 19; in 2 of them it appeared to be t(14;19) (q32;q13‐1). The third patient probably had the same translocation. All 3 patients had received therapy prior to cytogenetic analysis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom