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Testicular cancer and occupational exposure to polyvinyl chloride plastics: A case‐control study
Author(s) -
Hardell Lennart,
Malmqvist Nils,
Ohlson CarlGöran,
Westberg Håkan,
Eriksson Mikael
Publication year - 2004
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.11709
Subject(s) - polyvinyl chloride , testicular cancer , occupational exposure , medicine , cancer , environmental health , chemistry , organic chemistry
Exposure to polyvinyl chloride (PVC) plastics as a risk factor for testicular cancer was investigated. In total, 981 cases who were 20–75 years old and had reported to the Swedish Cancer Registry during 1993–1997 were included. One matched control from the population registry was used. Exposure was assessed by a questionnaire that was supplemented over the phone. Furthermore, an occupational hygienist qualified all exposures. In all, 791 matched pairs completed the questionnaire. Overall exposure to PVC plastics gave the odds ratio (OR)=1.35, 95% confidence interval (CI)=1.06–1.71, increasing with >10 year latency period to OR=1.45, 95% CI=1.06–1.98. No dose‐response relationships were found but rather an inverse relationship with the highest odds ratios in the lowest exposure category. In conclusion, no clear association with testicular cancer and exposure to PVC could be found in our study in contrast to a previous observation. © 2004 Wiley‐Liss, Inc.