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The effect of nabilone on neuropsychological functions related to driving ability: an extended case series
Author(s) -
Kurzthaler Ilsemarie,
Bodner Thomas,
Kemmler Georg,
Entner Tanja,
Wissel Joerg,
Berger Thomas,
Fleischhacker W. Wolfgang
Publication year - 2005
Publication title -
human psychopharmacology: clinical and experimental
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 78
eISSN - 1099-1077
pISSN - 0885-6222
DOI - 10.1002/hup.688
Subject(s) - neuropsychology , psychomotor learning , psychology , dronabinol , medicine , cannabinoid , physical medicine and rehabilitation , psychiatry , cognition , receptor
The primary goal of this prospective extended case series was to obtain the first data about the potential influence of nabilone intake on driving ability related neuropsychological functions. Six patients were investigated within a placebo controlled, double‐blind crossover study of this synthetic cannabinoid (2 mg/day) in patients with multiple sclerosis and spasticity associated pain. Five neuropsychological functions (reaction time, working memory, divided attention, psychomotor speed and mental flexibility) were assessed. No indication was found of a deterioration of any of the five investigated neuropsychological functions during the 4‐week treatment period with nabilone. Copyright © 2005 John Wiley & Sons, Ltd.