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Paroxetine treatment of delusional disorder, somatic type
Author(s) -
Hayashi Hiroshi,
Oshino Shingo,
Ishikawa Junichi,
Kawakatsu Shinobu,
Otani Koichi
Publication year - 2004
Publication title -
human psychopharmacology: clinical and experimental
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 78
eISSN - 1099-1077
pISSN - 0885-6222
DOI - 10.1002/hup.590
Subject(s) - delusion , paroxetine , delusional disorder , serotonergic , psychology , psychiatry , medicine , psychosis , serotonin , antidepressant , anxiety , receptor
A 77‐year‐old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared after 8 weeks. Hypoperfusion in the left temporal and parietal lobes which was observed when she had the delusion was normalized after resolution of the delusion. This report suggests that paroxetine may be effective for delusional disorder, somatic type. It also supports the previous views that this disorder is associated with serotonergic dysfunction and hypoperfusion in the temporal and parietal lobes. Copyright © 2004 John Wiley & Sons, Ltd.