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The release of oxytocin, vasopressin and associated neurophysins after electroconvulsive therapy
Author(s) -
Scott Allan I. F.,
Shering P. Anne,
Lightman Stafford L.,
Legros JeanJacques,
Whalley Lawrence J.
Publication year - 1991
Publication title -
human psychopharmacology: clinical and experimental
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 78
eISSN - 1099-1077
pISSN - 0885-6222
DOI - 10.1002/hup.470060211
Subject(s) - oxytocin , neurophysins , vasopressin , electroconvulsive therapy , endocrinology , medicine , neuropeptide , chemistry , receptor , electroconvulsive shock
Blood concentrations of oxytocin (OT), vasopressin (VP) and their associated neurophysins were measured before and after the first electroconvulsive therapy (ECT) given to 12 depressed patients. The maximum concentrations of all four peptides coincided at +2 min, but the increases in OT and VP were about four‐fold greater than their associated neurophysins. None of the peptide increases correlated with spike‐wave or total cerebral seizure activity as measured by electroencephalogram.