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Effect of clonazepam on tardive akathisia
Author(s) -
Kuniyoshi Masahiro,
Arikawa Katsuyoshi,
Miura Chishin,
Inanaga Kazutoyo
Publication year - 1991
Publication title -
human psychopharmacology: clinical and experimental
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 78
eISSN - 1099-1077
pISSN - 0885-6222
DOI - 10.1002/hup.470060107
Subject(s) - clonazepam , akathisia , medicine , anesthesia , psychiatry , antipsychotic , schizophrenia (object oriented programming)
Clonazepam was administered to nine patients with tardive akathisia which could not be controlled by antiparkinsonian drugs, and a good response was obtained in all cases. The daily dose of clonazepam given was only 1.0–3.0 mg. In two of the nine patients, akathisia recurred when the dose of clonazepam was reduced, but disappeared again after the dose was increased again. Clonazepam appears to be worth trying in patients with tardive akathisia, and is effective at relatively low doses. However, a dose reduction should be performed with caution, since there is the possibility that akathisia will recur.