Premium
A serotonin hypothesis of panic disorder
Author(s) -
Kahn Rene S.,
Van Praag Herman M.
Publication year - 1988
Publication title -
human psychopharmacology: clinical and experimental
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 78
eISSN - 1099-1077
pISSN - 0885-6222
DOI - 10.1002/hup.470030409
Subject(s) - panic disorder , panic , anxiety , serotonin , psychology , anxiety disorder , psychiatry , clinical psychology , neuroscience , medicine , receptor
Despite numerous animal studies indicating an important role of serotonin (5‐HT) in anxiety, 5‐HT's function in the regulation of human anxiety has hardly been studied. Recent clinical studies suggest an involvement of 5‐HT systems in panic disorder. This paper will briefly review the pertinent data on 5‐HT and panic disorder and propose a specific hypothesis on 5‐HT abnormalities in that disorder.