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A placebo‐controlled, double‐blind trial of Ginkgo biloba for antidepressant‐induced sexual dysfunction
Author(s) -
Kang ByungJo,
Lee SeungJae,
Kim MoonDoo,
Cho ManJe
Publication year - 2002
Publication title -
human psychopharmacology: clinical and experimental
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 78
eISSN - 1099-1077
pISSN - 0885-6222
DOI - 10.1002/hup.409
Subject(s) - ginkgo biloba , placebo , ginkgoales , antidepressant , medicine , double blind , sexual dysfunction , placebo group , sexual function , pharmacology , ginkgo , anesthesia , traditional medicine , biology , pharmacognosy , alternative medicine , biochemistry , pathology , hippocampus , biological activity , in vitro
The aim of this study was to examine the effect of Ginkgo biloba on antidepressant‐induced sexual dysfunction. The Ginkgo biloba ( n =19) and the placebo groups ( n =18) were divided; each to be administered with Ginkgo biloba and placebo respectively for 2 months by means of a randomized placebo‐controlled, double‐blind study. The results of this 2 month trial were: (1) there was no statistical significant difference from the placebo at weeks 2, 4 and 8 after medication; (2) in comparison with baseline, both the Ginkgo biloba group and the placebo group showed improvement in some part of the sexual function, which is suggestive of the importance of the placebo effect in assessing sexual function. This study did not replicate a prior positive finding supporting the use of Ginkgo biloba for antidepressant, especially SSRI, induced sexual dysfunction. Copyright © 2002 John Wiley & Sons, Ltd.