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Neurolymphomatosis—diagnosis and assessment of treatment response by FDG PET‐CT
Author(s) -
Lin M,
Kilanowska J,
Taper J,
Chu J
Publication year - 2008
Publication title -
hematological oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 44
eISSN - 1099-1069
pISSN - 0278-0232
DOI - 10.1002/hon.837
Subject(s) - medicine , biopsy , lymphoma , positron emission tomography , radiology , nuclear medicine , infiltration (hvac) , pet ct , pathology , physics , thermodynamics
Neurolymphomatosis (NL) is lymphomatous infiltration of peripheral nerves, and is an uncommon manifestation of non‐Hodgkin's lymphoma (NHL). Although nerve biopsy is the main method for histological diagnosis, a blind nerve biopsy may not be diagnostic. While CT and MRI have been used to detect NL, recent reports demonstrated the benefit of integrated positron emission tomography (PET) using F 18 ‐2‐fluoro‐2‐deoxy‐D‐glucose (FDG) combined with computed tomography (CT). We described the utility of FDG PET‐CT in this uncommon subgroup of NHL where it can assist in establishing the diagnosis, the potential to guide sites for biopsy and in the assessment of response to therapy. Copyright © 2007 John Wiley & Sons, Ltd.