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Prognostic value of serum beta 2 microglobulin in primary gastric lymphoma
Author(s) -
Avilés Agustin,
DíazMaqueo José C.,
Rodriguez Leticia,
García Edna L.,
Guzmán Renaldo,
Talavera Alejandra
Publication year - 1991
Publication title -
hematological oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 44
eISSN - 1099-1069
pISSN - 0278-0232
DOI - 10.1002/hon.2900090207
Subject(s) - beta 2 microglobulin , beta (programming language) , medicine , value (mathematics) , gastroenterology , mathematics , statistics , computer science , programming language
Sixty‐eight previously untreated patients with primary gastric non‐Hodgkin's lymphoma (NHL) available for analysis, were entered in a study in which the prognostic significance of serum beta 2 microglobulin levels were evaluated. The serum beta 2 microglobulin was the most significant prognostic factor. Patients with high levels (> 3.5 μg/mL) had a relapse‐free survival (RFS) of 36 months, while the median RFS has not been reached in patients with normal levels ( p <0.001). The 5‐year survival was 80 per cent for patients with normal levels, statistically significant when compared to patients with high levels: 38 per cent ( p > 0.001). Serum beta 2 microglobulin should be included in the initial staging of patients with primary extranodal NHL and patients with high levels should be treated more aggressively.