Normal B cell compartment in chronic lymphatic leukemia | Zendy

Pluta A. | Zendy; Górski A. | Zendy; Nowaczyk M. | Zendy; Modlińska M. | Zendy

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Normal B cell compartment in chronic lymphatic leukemia

Author(s) -

Pluta A.,

Górski A.,

Nowaczyk M.,

Modlińska M.

Publication year - 1990

Publication title -

hematological oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.918

H-Index - 44

eISSN - 1099-1069

pISSN - 0278-0232

DOI - 10.1002/hon.2900080302

Subject(s) - cd5 , compartment (ship) , chronic lymphocytic leukemia , immunofluorescence , chronic lymphatic leukemia , b cell , antigen , pathology , lymphatic system , leukemia , medicine , biology , immunology , antibody , oceanography , geology

In contrast to normal B lymphocytes, CLL cells express CD5 antigen believed to be a T cell marker. We have assessed normal and malignant B cell compartments in CLL patients with the aid of two‐colour immunofluorescence techniques (CD5‐TRITC, DR‐FITC). No clear correlation was found between progression of disease and parameters studied. However, there was a tendency for a diminution of normal B cells in advanced stages of disease.

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