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Aggressive angiofollicular lymph node hyperplasia (castleman's disease) treated with high dose melphalan and autologous bone marrow transplantation
Author(s) -
Repetto L.,
Jaiprakash M. P.,
Selby P. J.,
Gusterson B. A.,
Williams H. J. H.,
McElwain T. J.
Publication year - 1986
Publication title -
hematological oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 44
eISSN - 1099-1069
pISSN - 0278-0232
DOI - 10.1002/hon.2900040305
Subject(s) - melphalan , medicine , chemotherapy , transplantation , bone marrow , lymph node , surgery , hyperplasia , pathology
A case of aggressive widespread angiofollicular lymph node hyperplasia in a 42‐year‐old male, treated with high dose melphalan is presented. The disease had failed to enter a durable remission after chemotherapy. High dose melphalan with autologous bone marrow transplantation achieved a complete remission which has lasted for 15 months to date. This approach can be considered when other measures fail.