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Treatment of acute lymphoblastic leukemia in adults
Author(s) -
Barbui Tiziano,
Bassan Renato,
Chisesi Teodoro,
Battista Raffaele,
Cortelazzo Sergio,
Rodeghiero Francesco,
Capnist Giovanni,
D'emilio Anna,
Viero Piera,
Dini Enrico
Publication year - 1985
Publication title -
hematological oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 44
eISSN - 1099-1069
pISSN - 0278-0232
DOI - 10.1002/hon.2900030107
Subject(s) - medicine , vincristine , lymphoblastic leukemia , cyclophosphamide , dexamethasone , complete remission , leukocyte counts , leukemia , gastroenterology , surgery , pediatrics , chemotherapy
Thirty‐seven adult patients with acute lymphoblastic leukemia were treated with a protocol called HEAV'D including Adriamycin, Vincristine, l‐Asparaginase, Cyclophosphamide and Dexamethasone. The complete remission rate was 70 per cent. The median duration of remission was more than 30 months. Patients with initial leukocyte count below 20 000/mmc experienced a longer remission (median not reached) than patients with a leukocyte count above 20 000/mmc (median 10 months).