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A distinctive follicular hyperplasia in the acquired immune deficiency syndrome (AIDS) and the AIDS related complex
Author(s) -
Meyer Paul R.,
Yanagihara Eugene T.,
Parker John W.,
Lukes Robert J.
Publication year - 1984
Publication title -
hematological oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 44
eISSN - 1099-1069
pISSN - 0278-0232
DOI - 10.1002/hon.2900020403
Subject(s) - hyperplasia , follicular hyperplasia , follicular phase , immune system , medicine , immunology , pathology , endocrinology
The histological features of a distinctive follicular hyperplasia observed in twenty‐nine male patients with AIDS or the AIDS related complex are described. The group includes four patients with Kaposi's sarcoma, five with lymphoma, 16 with persistent generalized lymphadenopathy, and four with hemophilia. Histopathology is correlated with lymphocyte phenotyping and clinical findings and a model for the pathogenesis of this unique syndrome is presented.