Premium
Simian AIDS—Evidence for a retroviral etiology
Author(s) -
Gardner Murray,
Marx Preston,
Maul Don,
Osborn Kent,
Henrickson Roy,
Lerche Nick,
Munn Bob,
Bencken Betsy,
Bryant Marty
Publication year - 1984
Publication title -
hematological oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 44
eISSN - 1099-1069
pISSN - 0278-0232
DOI - 10.1002/hon.2900020305
Subject(s) - virology , retrovirus , simian , etiology , macaque , human immunodeficiency virus (hiv) , simian immunodeficiency virus , immunology , virus , biology , medicine , pathology , paleontology
This paper reviews the major features of a simian model of acquired immunodeficiency (‘SAIDS’), SAIDS occurs endemically in colonies of macaque monkeys in the United States and resembles AIDS in humans in overall clinical manifestations, pathology, and immune deficiency. An infectious type D retrovirus, related to but distinct from the Mason‐Pfizer monkey virus, has been identified as the primary cause of SAIDS. The relevance of these findings for human AIDS is discussed.