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A SELECTIVE AND COVALENT INHIBITOR OF ITK BLOCKS TCR SIGNALING, INHIBITS PROLIFERATION OF HUMAN SÉZARY CELLS IN VITRO, AND INDUCES TUMOR REGRESSION IN DOGS WITH T‐CELL LYMPHOMA
Author(s) -
Buggy J.J.,
Ng P.P.,
Janc J.W.,
Hotson A.,
Hill C.M.,
Thamm D.H.,
Kim Y.H.,
Khodadoust M.,
Mobasher M.,
Miller R.A.
Publication year - 2019
Publication title -
hematological oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 44
eISSN - 1099-1069
pISSN - 0278-0232
DOI - 10.1002/hon.129_2630
Subject(s) - t cell , cancer research , bruton's tyrosine kinase , biology , t cell receptor , immune system , cytotoxic t cell , cd28 , kinase , cd8 , immunology , tyrosine kinase , microbiology and biotechnology , in vitro , signal transduction , biochemistry