Premium
Die Spaltung von d , l ‐Muscarin in die optischen Antipoden. 10. Mitteilung über Muscarin
Author(s) -
Eugster C. H.,
Häfliger F.,
Denss R.,
Girod E.
Publication year - 1958
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.660410332
Subject(s) - chemistry , muscarine , tartaric acid , stereochemistry , salt (chemistry) , organic chemistry , biochemistry , receptor , muscarinic acetylcholine receptor , citric acid
With the aid of the two di‐p‐toluyl‐tartaric acids dl ‐Muscarine has been resolved into its optical antipodes. Contrary to the indicatitons of F.Kögl et al. H. C. Cox, E. Hardegger, F. Kog̈l, P. Liechti, F. Lohse & C. A . Salemink, Helv. 41,229 (1958(. the less soluble salt of the laevorotatory acid is that of the unnatural (−)‐muscarine; (+)‐muscarine, identical in physical and biological properties with the natural alcaloid, was obtained as the less soluble salt with (+)‐di‐p‐toluyl‐ L ‐tartaric acid.