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Über die Selektivität des Glycins bei der Hippursäurebildung. Der „Cyanid‐Effekt”︁
Author(s) -
Rottenberg Max
Publication year - 1958
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.660410135
Subject(s) - chemistry , cyanide , hippuric acid , hydrolysis , hydroxide , medicinal chemistry , glycine , organic chemistry , amino acid , biochemistry , urine
Experiments are described which establish the „cyanide effect”. In strongly alkaline solutions (hydroxide or carbonate) benzoylcholine undergoes hydrolysis but does not appreciably react with glycine. In the presence of cyanide, however, considerable amounts of hippuric acid are formed concurrent with hydrolysis.