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Facile Synthesis of Unsymmetrical Trialkoxysilanols: (RO) 2 (R′O)SiOH
Author(s) -
Docherty Scott R.,
Estes Deven P.,
Copéret Christophe
Publication year - 2018
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201700298
Subject(s) - chemistry , crystallization , imidazole , transition metal , metal , stereochemistry , combinatorial chemistry , crystallography , medicinal chemistry , organic chemistry , catalysis
Trialkoxysilanols, (RO) 3 SiOH, are useful as ligands in transition‐metal complexes because they provide models for silica‐supported metal sites or precursors for the thermolytic precursor approach. However, their synthesis is mostly limited to symmetrical ones, where all RO ligands are the same. However, unsymmetrically substituted trialkoxysilanols could offer significant advantages over their symmetrical counterparts by facilitating crystallization of complexes, lowering crystallographic disorder, changing the thermal properties of the complexes made, and making the addition of pendant functional groups possible. Herein, a simple, general synthetic procedure yielding unsymmetrical trialkoxysilanols (RO) 2 (R′O)SiOH is presented using imidazole as a promoter.