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Isocassiaoccidentalin B, A New C ‐Glycosyl Flavone Containing a 3‐Keto Sugar, and Other Constituents from Cassia nomame
Author(s) -
Syed Ahmed Shah,
Akram Muhammad,
Bae OkNam,
Kim Chul Young
Publication year - 2016
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201600131
Subject(s) - chemistry , cassia , glycosyl , flavonoid , sugar , glycoside , stereochemistry , organic chemistry , antioxidant , medicine , alternative medicine , pathology , traditional chinese medicine
A new C ‐glycosyl flavone containing a 3‐keto sugar, isocassiaoccidentalin B ( 1 ), was isolated from whole Cassia nomame ( Sieber ) Honda plants, along with eleven known compounds, including two flavonoids ( 2 and 3 ), five flavonoid glycosides ( 4 – 8 ), two chalcones ( 9 and 10 ), and two phenylpropanoids ( 11 and 12 ). The chemical structures of all compounds were determined via 1D‐ and 2D‐ NMR , and ESI ‐ MS . Among these, compounds 2 , 3 , 7 , and 8 were found to be the most potent in inhibiting nitric oxide release. Compounds 1 , 2 , 4 , 8 , 9 , and 10 showed significant free‐radical scavenging activity.