Isocassiaoccidentalin B, A New  C ‐Glycosyl Flavone Containing a 3‐Keto Sugar, and Other Constituents from  Cassia   nomame | Zendy

Syed Ahmed Shah | Zendy; Akram Muhammad | Zendy; Bae OkNam | Zendy; Kim Chul Young | Zendy

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Isocassiaoccidentalin B, A New C ‐Glycosyl Flavone Containing a 3‐Keto Sugar, and Other Constituents from Cassia nomame

Author(s) -

Syed Ahmed Shah,

Akram Muhammad,

Bae OkNam,

Kim Chul Young

Publication year - 2016

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201600131

Subject(s) - chemistry , cassia , glycosyl , flavonoid , sugar , glycoside , stereochemistry , organic chemistry , antioxidant , medicine , alternative medicine , pathology , traditional chinese medicine

A new C ‐glycosyl flavone containing a 3‐keto sugar, isocassiaoccidentalin B ( 1 ), was isolated from whole Cassia nomame ( Sieber ) Honda plants, along with eleven known compounds, including two flavonoids ( 2 and 3 ), five flavonoid glycosides ( 4 – 8 ), two chalcones ( 9 and 10 ), and two phenylpropanoids ( 11 and 12 ). The chemical structures of all compounds were determined via 1D‐ and 2D‐ NMR , and ESI ‐ MS . Among these, compounds 2 , 3 , 7 , and 8 were found to be the most potent in inhibiting nitric oxide release. Compounds 1 , 2 , 4 , 8 , 9 , and 10 showed significant free‐radical scavenging activity.

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