Lyciumaside and Lyciumate: A New Diacylglycoside and Sesquiterpene Lactone from  Lycium shawii | Zendy

Rehman Najeeb Ur | Zendy; Hussain Hidayat | Zendy; AlRiyami Samia Ahmed | Zendy; Csuk René | Zendy; Khiat Mohammed | Zendy; Abbas Ghulam | Zendy; AlRawahi Ahmed | Zendy; Green Ivan R. | Zendy; Ahmed Ishtiaq | Zendy; AlHarrasi Ahmed | Zendy

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Lyciumaside and Lyciumate: A New Diacylglycoside and Sesquiterpene Lactone from Lycium shawii

Author(s) -

Rehman Najeeb Ur,

Hussain Hidayat,

AlRiyami Samia Ahmed,

Csuk René,

Khiat Mohammed,

Abbas Ghulam,

AlRawahi Ahmed,

Green Ivan R.,

Ahmed Ishtiaq,

AlHarrasi Ahmed

Publication year - 2016

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201600066

Subject(s) - chemistry , sesquiterpene , sesquiterpene lactone , heteronuclear single quantum coherence spectroscopy , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , lycium , lactone , carbon 13 nmr , dept , medicine , alternative medicine , pathology

One new diacylglycoside named lyciumaside ( 1 ) and a new sesquiterpene lactone named lyciumate ( 2 ) were isolated from Lycium shawii Roem . & Schult . The structures of the two new compounds were elucidated based on 1D‐ ( 1 H‐ and 13 C‐ NMR and NOE ) and 2D‐ NMR ( COSY , HSQC , and HMBC ) spectroscopic techniques, and mass spectrometry ( ESI‐MS ). Preliminary evaluations demonstrated lyciumaside ( 1 ) possesses strong antioxidant activity with an IC 50 = 30 μg/ml (80% inhibition) while it was inactive in α ‐glucosidase and urease enzymes assays.

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