Premium
Two New Triterpenoid Glycosides from the Roots of Rosa cymosa Tratt .
Author(s) -
Ma GuoXu,
Huang XiaoYan,
Dai HuaNian,
Zhong XiaoQing,
Zhou YanLin,
Su ZuoLin,
He YingZi,
Yang JunShan,
Yuan JingQuan,
Xu XuDong
Publication year - 2016
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500548
Subject(s) - chemistry , triterpenoid , glycoside , stereochemistry , terpene
Two new triterpenoid glycosides, 3 α ,19 α ,23 α ‐trihydroxy‐2‐oxo‐12‐ursen‐28‐ O ‐ β ‐ d ‐glucopyranoside ( 1 ) and 3 α ,19 α ,23 α ‐trihydroxy‐2‐oxoolean‐12‐en‐28‐ O ‐ β ‐ d ‐glucopyranoside ( 2 ) as well as three known compounds, 2 α ,3 α ,19 α ‐trihydroxyolean‐12‐en‐28‐ O ‐ β ‐ d ‐glucopyranoside ( 3 ), 2 α ,3 α ,19 α ,23‐tetrahydroxy‐12‐ursen‐28‐ O ‐ β ‐ d ‐glucopyranoside ( 4 ), and 2 α ,3 β ,19 α ,23‐tetrahydroxyurs‐12‐en‐28‐oic acid ( 5 ) were isolated from 75% Et OH extract of Rosa cymosa . Their structures were elucidated by extensive spectroscopic methods. All the isolated compounds displayed moderate inhibitory activity against LPS ‐induced NO production in macrophages.