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Three New Chalcones from the Aerial Parts of Angelica keiskei
Author(s) -
Kil YunSeo,
Kwon Jaeyoung,
Lee Dongho,
Seo Eun Kyoung
Publication year - 2016
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500519
Subject(s) - chemistry , chalcone , traditional medicine , alcohol , stereochemistry , organic chemistry , medicine
Three new chalcones, 3′‐carboxymethyl‐4,2′‐dihydroxy‐4′‐methoxychalcone ( 1 ), (±)‐4,2′,4′‐trihydroxy‐3′‐[(3‐hydroxy‐2,2‐dimethyl‐6‐methylenecyclohexyl)methyl]chalcone ( 2 ), and 2′′‐hydroxyangelichalcone ( 3 ), were isolated from the aerial parts of Angelica keiskei (Umbelliferae) together with five known compounds, artocarmitin A ( 4 ), (+)‐ cis ‐(3′ R ,4′ R )‐methylkhellactone ( 5 ), (−)‐ trans ‐(3′ R ,4′ S )‐methylkhellactone ( 6 ), 3,4‐dihydroxanthotoxin ( 7 ), and ( Z )‐ p ‐coumaryl alcohol ( 8 ). The known compounds 4 – 8 were identified from A . keiskei for the first time. The structures of 1 – 3 were elucidated by interpreting spectroscopic data including 1D‐ and 2D‐NMR.