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Three New Atisane Diterpenoids from Spiraea japonica
Author(s) -
Qin XiangDong,
Yang Shu,
Zhao Yan,
Wang LiXia,
Ren FuCai,
Wang Fei
Publication year - 2016
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500282
Subject(s) - diterpene , stereochemistry , chemistry , japonica , botany , biology
Three new atisane diterpenoids, spiratisanins A – C ( 1 – 3 , resp.), featuring a phenylacryloxyl substituted ent ‐atisane skeleton, were isolated from Spiraea japonica together with two known atisine diterpene alkaloids, spiramine A ( 4 ) and spiradine F ( 5 ). The structures of these new compounds were elucidated as (5 β ,7 α ,8 α ,9 β ,10 α ,12 α ,16 β )‐16‐hydroxyatisan‐7‐yl (2 E )‐3‐phenylprop‐2‐enoate ( 1 ), (5 β ,7 α ,8 α ,9 β ,10 α ,12 α ,16 α )‐16‐hydroxyatisan‐7‐yl (2 E )‐3‐phenylprop‐2‐enoate ( 2 ), and (5 β ,8 α ,9 β ,10 α ,12 α ,16 β )‐16‐hydroxyatisan‐20‐yl (2 E )‐3‐phenylprop‐2‐enoate ( 3 ) on the basis of spectroscopic analysis.