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N , N′ ‐Bis(arylmethylidene)arylmethanediamines: Suitable Precursors for the Synthesis of 1‐Pyrroline Derivatives
Author(s) -
Alizadeh Abdolali,
Moafi Leila
Publication year - 2016
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500251
Subject(s) - chemistry , yield (engineering) , pyrroline , catalysis , elemental analysis , pyrrole , reaction conditions , proton nmr , combinatorial chemistry , medicinal chemistry , organic chemistry , materials science , metallurgy
A simple and appropriate procedure for the synthesis of 4,5‐dihydro‐5‐hydroxy‐3 H ‐pyrrole‐3,3‐dicarbonitrile derivatives is reported. The advantages of this method are one‐pot conditions, high yield of products, short reaction times, and no need of metal catalyst. The structures are confirmed spectroscopically (IR, 1 H‐ and 13 C‐NMR, and EI‐MS) and by elemental analyses. A plausible mechanism for this reaction is proposed ( Scheme 2 ).