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Antioxidative Cassane Diterpenoids from the Seeds of Caesalpinia minax
Author(s) -
Zhang JunSheng,
Guo YanQiong,
Bao JingMei,
Jiang MinHong,
Lin ShuLing,
Su ZhiYou,
Tang GuiHua,
Yin Sheng
Publication year - 2015
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500230
Subject(s) - chemistry , oxygen radical absorbance capacity , trolox , caesalpinia , antioxidant , organic chemistry , absorbance , stereochemistry , chromatography , antioxidant capacity , traditional medicine , medicine
Five new cassane diterpenoids, caesalmins I–M ( 1 – 5 ), and 23 known analogs were isolated from the seeds of Caesalpinia minax. Their structures were elucidated by spectroscopic methods and comparison with reported data. The antioxidant properties of 1 – 28 were determined by the method of oxygen radical absorbance capacity of fluorescein (ORAC‐FL), and 14 compounds exhibited good antioxidant activities with ORAC‐FL values of 2.24–4.89 Trolox equivalents. The structureactivity relationship of the active compounds was also discussed.