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Synthesis of Pseudo ‐Peptides Containing a Quinazolinone Skeleton via Ugi Four‐Component Reaction
Author(s) -
Balalaie Saeed,
Saeedi Shaghayegh,
Ramezanpour Sorour
Publication year - 2016
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500187
Subject(s) - chemistry , quinazolinone , ugi reaction , component (thermodynamics) , scope (computer science) , combinatorial chemistry , peptide , multi component reaction , carboxylic acid , stereochemistry , organic chemistry , isocyanide , biochemistry , catalysis , physics , computer science , thermodynamics , programming language
A simple and efficient synthesis of quinazolinone pseudo ‐peptide derivatives based on a new 3‐amino‐1,2,3,4‐tetrahydro‐4‐oxoquinazoline‐2‐carboxylic acid via Ugi four‐component reaction has been developed. This reaction was conducted under mild conditions with a broad scope of substrates.