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Subergane‐Type Sesquiterpenes from Gorgonian Coral Subergorgia suberosa with Antibacterial Activities
Author(s) -
Huang Qixi,
Cheng Wei,
Long Hailin,
Liu Huagang,
van Ofwegen Leen,
Lin Wenhan
Publication year - 2015
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500086
Subject(s) - gorgonian , chemistry , coral , sesquiterpene , stereochemistry , antibacterial activity , absolute configuration , terpene , terpenoid , bacteria , ecology , genetics , biology
A new subergane‐type sesquiterpene, named epoxysubergorgic acid ( 1 ), along with seven known sesquiterpenes, were isolated from the gorgonian coral Subergorgia suberosa. The structure of the new compound was determined by extensive spectroscopic analyses. The previously uncertain absolute configuration of the known analogues 2 – 6 was determined on the basis of CD, Mosher 's method, and through chemical conversions. All compounds were evaluated for antibacterial activities.