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Reductive Amination of ω ‐Oxoecdysteroids in the Synthesis of Dimeric Ecdysteroids
Author(s) -
Savchenko Rimma G.,
Kostyleva Svetlana A.,
Odinokov Victor N.
Publication year - 2015
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201500068
Subject(s) - chemistry , reductive amination , ethylenediamine , amination , alkyl , monomer , organic chemistry , medicinal chemistry , stereochemistry , polymer , catalysis
N ‐Alkyl‐ and N ‐arylaminoecdysteroids were synthesized for the first time by reductive amination of ω ‐oxoecdysteroids. By using aliphatic or aromatic diamines, dimeric ecdysteroids with an ethylenediamine or p ‐phenylenediamine bridge at the C(24), C(24′)‐position of the monomeric moieties were obtained.
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