Premium
Facile Synthesis of the Pentasaccharide Repeating Unit of the Exopolysaccharide from Cryptococcus neoformans Serotype D
Author(s) -
Zhuo XiaoBin,
Zou Yan,
Huang ShengJun,
Liao Jun,
Hu HongGang,
Zhao QingJie,
Wu QiuYe
Publication year - 2015
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201400297
Subject(s) - cryptococcus neoformans , chemistry , stereochemistry , glycoside , serotype , microbiology and biotechnology , biology
β ‐ D ‐Glc p A‐(1→2)‐[ β ‐ D ‐Xyl p ‐(1→2)‐ α ‐ D ‐Man p ‐(1→3)]‐ α ‐ D ‐Man p ‐(1→3)‐ α ‐ D ‐Man p , the repeating unit of the exopolysaccharide from Cryptococcus neoformans serotype D, was synthesized as its 4‐methoxyphenyl glycoside. The approach presented here also provides a route to the synthesis of more complex repeating units of glucuconoxylomannan (GXM) of C. neoformans serotypes A–C.