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Two New Triterpenoid Saponins from Stauntonia obovatifoliola Hayata ssp. intermedia
Author(s) -
Lu XuRan,
Wang XiaoMin,
Wang ZhiMin,
Chen XiaoQing,
Wang ManYuan,
Gong MuXin
Publication year - 2015
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201400174
Subject(s) - chemistry , triterpenoid , hederagenin , hela , intermedia , stereochemistry , saponin , biochemistry , cell , pathology , art , performance art , art history , medicine , alternative medicine
Two new hederagenin‐type saponins, staunoside G ( 1 ) and staunoside H ( 2 ), along with twelve known triterpenoid saponins, were isolated from stems of Stauntonia obovatifoliola Hayata ssp. intermedia. Their structures were determined by analysis of HR‐EI‐MS, and 1D‐ and 2D‐NMR data, and comparison with those in literature. The two new compounds showed moderate cytotoxicities against three tumor cells, i.e. , A549 (lung carcinoma), 4T1 (mammary carcinoma), and HeLa (cervical carcinoma).