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Tandem Benzylic Oxidation/Dihydroxylation of α ‐Vinyl‐ and α ‐Alkenylbenzyl Alcohols
Author(s) -
Fernandes Rodney A.,
Kattanguru Pullaiah
Publication year - 2015
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201400143
Subject(s) - chemistry , dihydroxylation , tandem , organic chemistry , substrate (aquarium) , alcohol oxidation , oxidative phosphorylation , enantioselective synthesis , alcohol , catalysis , biochemistry , composite material , materials science , oceanography , geology
A de novo tandem benzylic oxidative dihydroxylation of α ‐vinyl‐ and α ‐alkenylbenzyl alcohols has been developed to give α , β ‐dihydroxypropiophenones (=2,3‐dihydroxy‐1‐phenylpropan‐1‐ones) and α , β ‐dihydroxyalkyl phenones. This method was shown to be substrate‐selective and specific for the oxidation of benzylic alcohols.