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New Route for the Synthesis of Four‐Membered Cyclic Ketene Dithioacetals
Author(s) -
Habibi Azizollah,
Valizadeh Yousef,
Alizadeh Abdolali
Publication year - 2015
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201400127
Subject(s) - ketene , chemistry , methylene , regioselectivity , condensation , alkyl , elemental analysis , medicinal chemistry , organic chemistry , catalysis , physics , thermodynamics
Abstract Novel ketene dithioacetals have been synthesized by a one‐pot condensation reaction of active methylene compounds with CS 2 in the presence of alkyl acetylenecarboxylates. This reaction proceeds in a regioselective manner and provides products in good yields. The structures of the ketene dithioacetals were characterized by IR, 1 H‐ and 13 C‐NMR, and MS data, and elemental analyses.