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Two New C ‐ seco Limonoids from the Fruit of Melia azedarach
Author(s) -
Jin Qinghao,
Lee Chul,
Woo Lee Jin,
Yeon Choi Jeong,
Tae Hong Jin,
Kim Youngsoo,
Kyeong Lee Mi,
Yeon Hwang Bang
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201400045
Subject(s) - melia azedarach , chemistry , limonoid , meliaceae , phytochemical , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , terpene , traditional medicine , triterpenoid , biochemistry , medicine
A phytochemical investigation of the fruits of Melia azedarach led to the isolation of two new C‐ seco ‐nimbolinin‐type limonoids, 3 α ‐acetoxy‐1 α ,7 α ‐dihydroxy‐12 α ‐methoxynimbolinin ( 1 ) and 3 α ‐acetoxy‐1 α ,12 α ‐dihydroxy‐7 α ‐(2‐methylprop‐2‐enoyl)nimbolinin ( 2 ), together with eleven known compounds, 3 – 13 . Their structures were elucidated on the basis of extensive spectroscopic analysis, including 1 H‐ and 13 C‐NMR, HMQC, HMBC, NOESY, and HR‐FAB‐MS.