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A New Stereoselective Total Synthesis of Phomonol
Author(s) -
Subba Reddy Basi V.,
Srinivas Lavudia,
Sivaramakrishna Reddy Pathuri,
Phaneendra Reddy Bhemavarapu,
Prasad Attaluri R.,
Yadav Jhillu S.
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300458
Subject(s) - chemistry , stereoselectivity , enantioselective synthesis , intramolecular force , total synthesis , tartaric acid , stereochemistry , michael reaction , combinatorial chemistry , organic chemistry , catalysis , citric acid
A stereoselective total synthesis of phomonol, following organocatalytic enantioselective epoxidation and intramolecular oxa‐ Michael reaction as key steps, is described. The use of readily available D ‐tartaric acid as a chiral source renders this approach quite simple and attractive.